Product name:TERT-BUTYL 5-OXO-2-AZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE
MF:C11H17NO3

MW: 211.26
Cas No.:198835-06-2
Structure:

Purity:95%

Product use:Basic raw materials, organic intermediates, pharmaceutical intermediates

The synthetic route is as follows:

diborane;

Reactants are commercially availlable.
Slade, David J., US2011/144150, A1, (2011) In a method analogous to J.Malpass and C. Cox, Tetrahedron Lett., 1999, 40, 1419-1422, tert-butyl 2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate is treated with diborane to afford a mixture of alcohols w hich is separated by chromatography.The desired alcohol tert-butyl 5-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate is then oxidized using the Swern procedure to afford the title compound.